In which trimester is the risk of developing gestational diabetes highest?

The risk of developing gestational diabetes is highest during the third trimester. During this period, the placenta produces increased amounts of hormones, such as cortisol and human placental lactogen, which can interfere with the action of insulin. As the pregnancy progresses, the body may find it increasingly difficult to maintain normal blood glucose levels due to these hormonal changes, leading to insulin resistance. This is particularly significant in the late stages of pregnancy, as the demands of the growing fetus increase and maternal metabolism becomes more altered.

While gestational diabetes can be diagnosed in the second trimester as well, the majority of cases are identified in the later part of pregnancy, which is why the third trimester is considered the peak time for the risk of developing this condition.